ChloroquineV1, Main, Exploration, bibRecord, 000188

Chloroquine differentially modulates coronary vasodilation in control and diabetic mice.

Identifieur interne : 000188 ( Main/Exploration ); précédent : 000187; suivant : 000189

Chloroquine differentially modulates coronary vasodilation in control and diabetic mice.

Auteurs : Qian Zhang [États-Unis] ; Atsumi Tsuji-Hosokawa [États-Unis] ; Conor Willson [États-Unis] ; Makiko Watanabe [États-Unis] ; Rui Si [États-Unis] ; Ning Lai [États-Unis] ; Ziyi Wang [États-Unis] ; Jason X-J Yuan [États-Unis] ; Jian Wang [États-Unis] ; Ayako Makino [États-Unis]

Source :

British journal of pharmacology [ 1476-5381 ] ; 2020.

RBID : pubmed:31503328

Abstract

Chloroquine is a traditional medicine to treat malaria. There is increasing evidence that chloroquine not only induces phagocytosis but regulates vascular tone. Few reports investigating the effect of chloroquine on vascular responsiveness of coronary arteries have been made. In this study, we examined how chloroquine affected endothelium-dependent relaxation in coronary arteries under normal and diabetic conditions.

DOI: 10.1111/bph.14864
PubMed: 31503328

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Chloroquine is a traditional medicine to treat malaria. There is increasing evidence that chloroquine not only induces phagocytosis but regulates vascular tone. Few reports investigating the effect of chloroquine on vascular responsiveness of coronary arteries have been made. In this study, we examined how chloroquine affected endothelium-dependent relaxation in coronary arteries under normal and diabetic conditions.</div>
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Serveur d'exploration Chloroquine

Chloroquine differentially modulates coronary vasodilation in control and diabetic mice.

Chloroquine differentially modulates coronary vasodilation in control and diabetic mice.

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Abstract

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